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Cuc B also triggers ATM-activated p53-14-3-3-σ pathways
Smiles: N#C/C(=C\C1=CC(O)=C(O)C=C1)/C(=O)NCCCC1C=CC=CC=1
3-Methyladenine induces cell death is independent of autophagy inhibition
Epub 2012 Sep 28
TPh A TI-277 Cuc B also triggers ATM-activatedTPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0. 6 uM. TPh A disrupts the formation of the bcl3pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells. Product information CAS Number: 21306 65 0 Molecular Weight: 399. 53 Formula: C21H21NO3S2 Chemical Name: N {[4 (benzyloxy)phenyl](methyl) sulfanylidene} 4 methylbenzene 1 sulfonamide
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