COCCCCOC1C=CC(=CC=1)C1C=CC(=CC=1)N1C(=S)N(C(=O)C1(C)C)C1=CC(=C(C=C1)C#N)C(F)(F)F)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1C](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M18325_1635156420.gif?v=1635156421)
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Smiles: CC(C)(C)[C@H](NC(=O)COCCCCOC1C=CC(=CC=1)C1C=CC(=CC=1)N1C(=S)N(C(=O)C1(C)C)C1=CC(=C(C=C1)C#N)C(F)(F)F)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1C
InChi: InChI=1S/C14H14O5S/c1-18-10-5-8-6-13(9(15)3-4-14(16)17)20-12(8)7-11(10)19-2/h5-7H
this agent is readily taken up by pancreatic beta cells
InChiKey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
CC-223 15789 Smiles: CC(C)(C)[C@H](NC(=O)COCCCCOC1C=CC(=CC=1)C1C=CC(=CC=1)N1C(=S)N(C(=O)C1(C)C)C1=CC(=C(C=C1)C#N)C(F)(F)F)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(=CC=1)C1SC=NC=1CCC 223 is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM. CC 223 inhibits both mTORC1 and mTORC2. Product information CAS Number: 1228013 30 6 Molecular Weight: 397. 47 Formula: C21H27N5O3 Chemical Name: 7 [6 (2 hydroxypropan 2 yl)pyridin 3 yl] 1 [(1r,4r) 4 methoxycyclohexyl] 1H,2H,3H,4H pyrazino[2,3 b][1,4]diazin 2 one Smiles:
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