YHO-13351 free base ie2 kinase inhibitor Smiles: NC(N)=NCCCCC(=O)NC1=CC(=CC(NC(=O)C2=CC(=NC=N2)C(=O)NC2=CC(=CC(NC(=O)CCCCN=C(N)N)=C2O[C@H]2CNCC2)C(F)(F)F)=C1O[C@H]1CNCC1)C(F)(F)F

Smiles: NC(N)=NCCCCC(=O)NC1=CC(=CC(NC(=O)C2=CC(=NC=N2)C(=O)NC2=CC(=CC(NC(=O)CCCCN=C(N)N)=C2O[C@H]2CNCC2)C(F)(F)F)=C1O[C@H]1CNCC1)C(F)(F)F

CH4O3S/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21

11(8):1437-1438

Smiles: C[C@H](CC1=CC(C(N)=O)=C2C(CCN2CCCO)=C1)NCCOC1=CC=CC=C1OCC(F)(F)F

YHO-13351 free base ie2 kinase inhibitor Smiles: NC(N)=NCCCCC(=O)NC1=CC(=CC(NC(=O)C2=CC(=NC=N2)C(=O)NC2=CC(=CC(NC(=O)CCCCN=C(N)N)=C2O[C@H]2CNCC2)C(F)(F)F)=C1O[C@H]1CNCC1)C(F)(F)FYHO 13351 free base is the prodrug of YHO 13177, which is a potent and specific inhibitor of BCRP. Product information CAS Number: 912288 64 3 Molecular Weight: 483. 62 Formula: C26H33N3O4S Chemical Name: (Z) 1 (5 (2 cyano 2 (3, 4 dimethoxyphenyl)vinyl)thiophen 2 yl)piperidin 4 yl diethylglycinate Smiles: COC1=CC=C(C=C1OC) C(=C C1=CC=C(S1)N1CCC(CC1)OC(=O)CN(CC)CC) C#N InChiKey: STLNUMIUXISGQQ HMMYKYKNSA N InChi: InChI=1S C26H33N3O4S c1 5 28(6 2)18