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PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid CK-636 prevents actin polymerization and

SKU: 33467044372

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Description

CK-636 prevents actin polymerization and the formation of actin filament comet tails by Listeria in infected SKOV3 cells (IC50=22 µM)

2% Tween-80 (MCT))

GW501516 is shown to be the most potent and selective PPARα agonists known with an EC50 of 1

increase in extracellular acidification rate

PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid CK-636 prevents actin polymerization andPKC IN 1, CAS No. 1046787 18 1, is a potent, ATP competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5. 3 and 10. 4 nM for human PKC and PKC, and IC50s of 2. 3, 8. 1, 7. 6, 25. 6, 57. 5, 314, 808 nM for PKC, PKCI, PKCII, PKC, PKC, PKC mu and PKC, respectively. IC50: 2. 3 nM (Human PKC), 7. 6 nM (Human PKCII), 8. 1 nM (Human PKCI), 25. 6 nM (Human PKC), 57. 5 nM (Human PKC), 314 nM (Human PKC mu), 808 nM (Human PKC) Ki: 5. 3 nM

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