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GS 5734-metabolite
is a potent small molecule to selectively eliminate human pluripotent stem cells/hPSCs while sparing a large array of tissue-specific stem/progenitor and differentiated cells
KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion
Hildebrand JM
PHA-767491 Hydrochloride - CAS# 942425-68-5 noxerine GS 5734-metabolitePHA 767491, also known as CAY10572, is a potent, ATP competitive dual cdc7 cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. PHA 767491 Suppresses Hepatocarcinoma Synergistically with 5 Fluorouracil. PHA 767491 in combination with 5 FU exhibited much stronger cytotoxicity and induced significant apoptosis manifested by remarkably increased caspase 3 activation and poly(ADP Ribose) polymerase