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Epub 2016 Apr 18
It has a half-life in circulation of around 30 seconds
and neurodegenerative diseases
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PZM21 - CAS# 1997387-43-5 chloride hydrate(x) Epub 2016 Apr 18PZM21 is a potent Gi activator with exceptional selectivity for OR and minimal arrestin 2 recruitment. PZM21 is an experimental opioid analgesic drug that is being researched for the treatment of pain. It is a functionally selective opioid receptor agonist which produces opioid receptor mediated G protein signaling, with potency and efficacy similar to morphine, but with less arrestin 2 recruitment. In tests on mice, PZM21 was slightly less potent
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