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BCT197 is an oral low-molecular-weight p38 inhibitor currently in development for the treatment of several inflammatory conditions
a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform
CAS Number: 1610964-64-1
Chemical Name: 2-amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2
Z-DQMD-FMK 17517 BCT197 is an oral low-molecular-weightInhibition of caspase 3 processing by Z DQMD FMK (Z Asp(OMe) Gln Met Asp(OMe) fluoromethylketone) did not restore cell number in the zinc deficient group, but resulted in processing of full length PKC to a 56 kDa fragment1. The inhibitory effect of specific caspase inhibitors (Z DQMD FMK, Z IETD FMK and Z LEHD FMK) suggests that the MG132 induced apoptotic cell death and depletion of GSH in SCLC cells are mediated by both activation of caspase 8 and
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