AC-4-130 Catalog No.:M31939-C 3'-triiodothyronin (T3) (10-7 M)

3'-triiodothyronin (T3) (10-7 M)

InChi: InChI=1S/C11H12BrNO3S/c1-16-11(15)9(6-17)13-10(14)7-2-4-8(12)5-3-7/h2-5

Treatment with Dalcetrapib markedly increases serum levels of HDL-C

InChi: InChI=1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13

AC-4-130 Catalog No.:M31939-C 3'-triiodothyronin (T3) (10-7 M)AC 4 130 is a potent STAT5 SH2 domain inhibitor. AC 4 130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5 dependent gene transcription. AC 4 130 induces cell cycle arrest and apoptosis in FLT3 ITD driven leukemic cells. AC 4 130 has anti cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML). Product information CAS Number: 1834571 82 2