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a clear dose-dependent anti-tumour effect is observed
from 10 to 100 mg/kg
1986 Feb 1
Addition of exogenous TNFα can significantly enhance the activity of these Smac mimetics
ELN318463 racemate osanin C a clear dose-dependent anti-tumour effectELN318463 racemate is the racemate of ELN318463. ELN318463 is an amyloid precursor protein (APP) selective secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1) and PS2 comprised secretase with EC50s of 12nM and 656 nM for PS1and PS2, respectively. ELN318463 is 51 fold more selective for PS1. Product information CAS Number: 851599 82 1 Molecular Weight: 471. 80 Formula: C19H20BrClN2O3S Chemical Name: N [(4