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CID-6451149
being 14- and 24-fold less active compared with HER2
regulate the expression of apoptotic proteins Bcl-2
Formula: C36H45NO7
BMS-564929 0364 CID-6451149BMS 564929 is a highly potent, orally active, nonsteroidal tissue selective androgen receptor (AR) modulator. BMS 564929 is a subnanomolar AR agonist in vitro, is highly selective for the AR vs. other steroid hormone receptors, and exhibits no significant interactions with SHBG or aromatase. Dose response studies in castrated male rats show that BMS 564929 is substantially more potent than testosterone (T) in stimulating the growth of the levator ani
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