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Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used for MI-389 (compound 22) synthesis
InChiKey: YZMCKZRAOLZXAZ-UHFFFAOYSA-N
6(7):517–519
Formula: C14H20BrN4NaO12PS
KDM5A-IN-1 Size:Contact [email protected] for quotation Thalidomide-NH-C6-NH-Boc is a synthesized E3KDM5A IN 1 is a potent, orally bioavailable pan histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A IN 1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B). Product information CAS Number: 1905481 36 8 Molecular Weight: 290. 36 Formula: C15H22N4O2 Chemical Name: N [(3R) 1 [3 (propan 2 yl) 1H
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