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Glucose-conjugated MGMT inhibitor - CAS# 382607-78-5 Catalog No.:M10751-2 Smiles: COC1C=C(O)C=C2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)C=12)C(=O)OC)C1C=CC=CC=1)C1C=CC(=CC=1)OC

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Description

Smiles: COC1C=C(O)C=C2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)C=12)C(=O)OC)C1C=CC=CC=1)C1C=CC(=CC=1)OC

and plays a pivotal role in the pathophysiology of a number of diseases

5-trihydroxyoxan-2-yl]oxy}-6-oxatetracyclo[11

nuclear factor erythroid-2-related factor 2/hemeoxygenase-1 signaling pathways

Glucose-conjugated MGMT inhibitor - CAS# 382607-78-5 Catalog No.:M10751-2 Smiles: COC1C=C(O)C=C2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)C=12)C(=O)OC)C1C=CC=CC=1)C1C=CC(=CC=1)OCO6BTG octylglucoside is a potent O6 methylguanine DNAmethyl transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. Product information CAS Number: 382607 78 5 Molecular Weight: 616. 53 Formula: C24H34BrN5O7S Synonym: O6BTG C8 Glu Chemical Name: (2R,3R,4S,5S,6R) 2 [(8 {2 amino 6 [(4 bromothiophen 2 yl)methoxy] 9H purin 9 yl}octyl)oxy] 6 (hydroxymethyl)oxane 3,4,5 triol Smiles:

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