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Smiles: CC1C=C(N2N=C(C)C(=C2N=1)C1=CC=C(OC)C(F)=C1F)C(F)(F)F
Molecular Weight: 188
CAS Number: 1807530-06-8
Exherin TFA salt
Platensimycin e chloride hydrate Smiles: CC1C=C(N2N=C(C)C(=C2N=1)C1=CC=C(OC)C(F)=C1F)C(F)(F)FPlatensimycin is an antibiotic produced by S. platensis that inhibits gram positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0. 1 M). Platensimycin targets the ketoacyl acyl carrier protein synthase I II, FabF B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S. aureus and E. coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
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