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14-prostaglandin J2 activates PPARδ’s transcriptional activity through formation of a covalent adduct between its endocyclic enone at C9 and Cys249 in the receptor’s ligand-binding domain
SCH 79797 protects against ischemia/reperfusion-induced arrhythmias in the rat hearts
Formula: C21H28N6O3S2
Chemical Name: potassium
Gefitinib-d3 - CAS# 1173976-40-3 Size:Contact [email protected] for quotation 14-prostaglandin J2 activates PPARδ’s transcriptionalGefitinib d3 (ZD1839 d3) is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity. Product information CAS Number: 1173976 40 3 Molecular