BML-284 HCl - CAS# 2095432-75-8 60286 Reduced SMAD7 leads to overactivation

Reduced SMAD7 leads to overactivation of TGF-beta signaling in MDS that can be reversed by a specific inhibitor of TGF-beta receptor I kinase

CAS Number: 1450833-55-2

2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12

62(12):1200-13

BML-284 HCl - CAS# 2095432-75-8 60286 Reduced SMAD7 leads to overactivationBML 284 HCl, CAS No. 2095432 75 8, also known as AMBMP and Wnt agonist 1, is a potent and selective activator of Wnt signaling. It enhances beta catenin and increases transcript and protein levels of p gp. Product information CAS Number: 2095432 75 8 Molecular Weight: 386. 83 Formula: C19H19ClN4O3 Synonym: BML284 HCl AMBMP HCl Wnt Agonist Chemical Name: 4 N (1,3 Benzodioxol 5 ylmethyl) 6 (3 methoxyphenyl)pyrimidine 2,4 diamine Hydrochloride Smiles: