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Chemical Name: (2R)-N-(4-{1-[6-(hydroxycarbamoyl)hexyl]-4-(morpholin-4-yl)-1H-pyrazolo[3
Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug
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5-difluorobenzenesulfonyl)phenyl]methyl}imidazo[1
GPI-1046 - CAS# 186452-09-5 020 Chemical Name: (2R)-N-(4-{1-[6-(hydroxycarbamoyl)hexyl]-4-(morpholin-4-yl)-1H-pyrazolo[3GPI 1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc core. GPI 1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models. GPI 1046 readily crosses the blood brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with
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