Cetirizine dihydrochloride thine HCl H2O β-lactam antibiotic which inhibits the

β-lactam antibiotic which inhibits the synthesis of peptidoglycan

PubMed Central PMCID: PMC2780427

MP-470 also inhibits c-Kit and PDGFRα

Nielsen EØ

Cetirizine dihydrochloride thine HCl H2O β-lactam antibiotic which inhibits theCetirizine hydrochloride is a potent second generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects.