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AMG-333 0172 Polianova MT

SKU: 60724882390

4.1
USD120.00 USD168.00

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Description

Polianova MT

InChi: InChI=1S/C23H24ClFN4O3/c1-13(2)17-10-27-21(16-7-14(24)3-4-19(16)25)8-22(17)29-20-5-6-26-9-18(20)23(32)28-15(11-30)12-31/h3-10

O=S(=O)(NC1CCNCC1)C1=CC(=CC=C1C(F)(F)F)S(=O)(=O)C1=CC=CC=C1

C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1

AMG-333 0172 Polianova MTAMG 333 is a potent and highly selective antagonist of TRPM8 with IC50 values of 13 nM and 30 nM for human TRPM8 and rat TRPM8. Product information CAS Number: 1416799 28 4 Molecular Weight: 453. 32 Formula: C20H12F5N3O4 Chemical Name: 6 ({[3 fluoro 4 (trifluoromethoxy)phenyl](3 fluoropyridin 2 yl)methyl}carbamoyl)pyridine 3 carboxylic acid Smiles: OC(=O)C1=CN=C(C=C1)C(=O)NC(C1N=CC=CC=1F)C1=CC(F)=C(C=C1)OC(F)(F)F InChiKey: QEBYISWYMFIXOZ UHFFFAOYSA N

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