MK-4827 Racemate Size:Contact [email protected] for quotation 3 μM and 4 μM

3 μM and 4 μM in cell-free assays

InChi: InChI=1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5

PU-H71 (30 n M) significantly reduces NOS2 activity (60% reduction) and expression in LI (1 μg/mL LPS and 5 ng/mL IFN γ)-stimulated astrocytes via inhibiting NF-κB element activation

5-trihydroxyoxan-2-yl]oxy}-6-oxatetracyclo[11

MK-4827 Racemate Size:Contact [email protected] for quotation 3 μM and 4 μMMK 4827 racemate (Niraparib racemate) is a selective inhibitor of PARP1 2 with IC50 of 3. 8 nM 2. 1 nM; >330 fold selective against PARP3, V PARP and Tank1. Product information CAS Number: 1038915 75 1 Molecular Weight: 320. 39 Formula: C19H20N4O Chemical Name: 2 [4 (piperidin 3 yl)phenyl] 2H indazole 7 carboximidic acid Smiles: N=C(O)C1=CC=CC2=CN(N=C21)C1C=CC(=CC=1)C1CNCCC1 InChiKey: PCHKPVIQAHNQLW UHFFFAOYSA N InChi: InChI=1S C19H20N4O c20 19(24)17