Rivaroxaban (Xarelto) yl)ethane-1 2-diamine hydrochloride APTO-253 is also an inducer

APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4)

Bardenhagen JP

Smiles: NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F

2015 Jan 8

Rivaroxaban (Xarelto) yl)ethane-1 2-diamine hydrochloride APTO-253 is also an inducerRivaroxaban, also known as BAY 59 7939, is an oral anticoagulant invented and manufactured by Bayer; in a number of countries it is marketed as Xarelto. If approved by the United States FDA, it will be marketed by Ortho McNeil Pharmaceutical. It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects lasts 812 hours, but