ML216 shows strong selectivity for BLM in cultured cells
PF-06447475 inhibits LRRK2 enzyme and LRRK2 in the whole cell assay with IC50s of 3 and 25 nM
The half-life of VX-702 is 16 to 20 hours
Nature Chem Biol
Roxithromycin Catalog No.:M9039-2 ML216 shows strong selectivity forRoxithromycin is a semi synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Product information CAS Number: 80214 83 1 Molecular Weight: 837. 05 Formula: C41H76N2O15 Synonym: Roxar Rulide Roxl 150 Chemical Name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R) 6 {[(2S,3R,4S,6R) 4 (dimethylamino) 3 hydroxy 6 methyloxan 2 yl]oxy} 14 ethyl 7,12,13 trihydroxy 4 {[(2R,4R,5S,6S) 5 hydroxy 4 methoxy 4,6